TUB antibody

CAT: 0710-FNab09099Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab09099Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro) . May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity) . Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.

Synonyms

Tubby protein homolog|TUB

Gene ID

7275

UniProt

P50607

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Tubby homolog

Target

TUB

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Neuroscience, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IP: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

56 kDa, 62 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

UniProtKB · P50607

Tubby protein homolog

TUB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P50607
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: TUB
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: D3DQU4, O00293, Q6B007

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmMembraneNucleusSecreted

Disease

Obesity

Biological process

PhagocytosisSensory transduction

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