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TRPC4AP antibody

CAT: 0710-FNab09017Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab09017Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX (TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca (2+) storage reduction in response to CHRM1.
Synonyms
Short transient receptor potential channel 4-associated protein (Trp4-associated protein, Trpc4-associated protein) |Protein TAP1|TNF-receptor ubiquitous scaffolding/signaling protein (Protein TRUSS) |TRPC4AP|C20orf188|TRRP4AP
Gene ID
26133
UniProt
Q8TEL6
Host
Mouse
Reactivity
Human
Immunogen
Transient receptor potential cation channel, subfamily C, member 4 associated protein
Target
TRPC4AP
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:500-1:5000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
91 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
1C0
Tested Applications
ELISA, WB, IHC

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