TRPC4 antibody

• Background :

  Form a receptor-activated non-selective calcium permeant cation channel. Acts as a cell-cell contact-dependent endothelial calcium entry channel. Probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Mediates cation entry, with an enhanced permeability to barium over calcium. May also be activated by intracellular calcium store depletion.

• Synonyms :

  Short transient receptor potential channel 4 (TrpC4) |Trp-related protein 4 (hTrp-4, hTrp4) |TRPC4

• Gene ID :

  7223

• UniProt :

  Q9UBN4

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Transient receptor potential cation channel, subfamily C, member 4

• Target :

  TRPC4

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:5000; IHC: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  112 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC