TRAF3IP1 antibody

• Background:

  Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels (PubMed:26487268) . Involved in ciliogenesis (By similarity) .

• Synonyms:

  TRAF3-interacting protein 1|Interleukin-13 receptor alpha 1-binding protein 1|Intraflagellar transport protein 54 homolog|Microtubule-interacting protein associated with TRAF3 (MIP-T3) |TRAF3IP1|IFT54|MIPT3

• Gene ID:

  26146

• UniProt:

  Q8TDR0

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  TNF receptor-associated factor 3 interacting protein 1

• Target:

  TRAF3IP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, IP, WB, IF, IHC

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  83 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, IP, WB, IF, IHC