TPRKB antibody

• Background :

  Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t (6) A activity of the complex. TPRKB is not required for tRNA modification (By similarity) .

• Synonyms :

  EKC/KEOPS complex subunit TPRKB|PRPK-binding protein|TP53RK-binding protein|TPRKB

• Gene ID :

  51002

• UniProt :

  Q9Y3C4

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  TP53RK binding protein

• Target :

  TPRKB

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Signal Transduction

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  20 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB