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TNFSF13 antibody

CAT: 0710-FNab08828Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08828Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
Synonyms
Tumor necrosis factor ligand superfamily member 13|A proliferation-inducing ligand (APRIL) |TNF- and APOL-related leukocyte expressed ligand 2 (TALL-2) |TNF-related death ligand 1 (TRDL-1) |TNFSF13|APRIL|TALL2|ZTNF2
Gene ID
8741
UniProt
O75888
Host
Rabbit
Reactivity
Human
Immunogen
Tumor necrosis factor (ligand) superfamily, member 13
Target
TNFSF13
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: :1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · O75888

Tumor necrosis factor ligand superfamily member 13

TNF13_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75888
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TNFSF13
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8MYD5, B4DVT2, Q541E1, Q5U0G8, Q96HV6, Q9P1M8, Q9P1M9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Molecular function

Cytokine

Biological process

Immunity

Cellular component

Secreted

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