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TMPRSS6 antibody

CAT: 0710-FNab08808Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08808Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HFE2, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.
Synonyms
Transmembrane protease serine 6|Matriptase-2|TMPRSS6
Gene ID
164656
UniProt
Q8IU80
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transmembrane protease, serine 6
Target
TMPRSS6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB