TMPRSS2 antibody

CAT: 0710-FNab08804Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08804Size:100 µg
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Background
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms
Transmembrane protease serine 2|Serine protease 10|Transmembrane protease serine 2 non-catalytic chain|Transmembrane protease serine 2 catalytic chain|TMPRSS2|PRSS10
Gene ID
7113
UniProt
O15393
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transmembrane protease, serine 2
Target
TMPRSS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
Immunogen Sequence
110-360aa, extra-cellular domain

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