TLE3 antibody

• Background:

  Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES (By similarity) .

• Synonyms:

  Transducin-like enhancer protein 3|Enhancer of split groucho-like protein 3 (ESG3) |TLE3|KIAA1547

• Gene ID:

  7090

• UniProt:

  Q04726

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Transducin-like enhancer of split 3 (E (sp1) homolog, Drosophila)

• Target:

  TLE3

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Applications:

  ELISA, WB, IHC, IP

• Field of Research:

  Stem Cells, Signal Transduction, Metabolism, Developmental biology

• Purification:

  Protein A+G purification

• Dilution:

  WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  90 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Clone ID:

  8D6

• Tested Applications:

  ELISA, WB, IHC, IP