TLE1 antibody

CAT: 0710-FNab08720Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08720Size:100 µg
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Background
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Synonyms
Transducin-like enhancer protein 1|E (Sp1) homolog|Enhancer of split groucho-like protein 1 (ESG1) |TLE1
Gene ID
7088
UniProt
Q04724
Host
Mouse
Reactivity
Human
Immunogen
Transducin-like enhancer of split 1 (E (sp1) homolog, Drosophila)
Target
TLE1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8F4
Tested Applications
ELISA, WB, IHC

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