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TIPIN antibody

CAT: 0710-FNab08716Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08716Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHEK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. Forms a complex with TIMELESS and this complex regulates DNA replication processes under both normal and stress conditions, stabilizes replication forks and influences both CHEK1 phosphorylation and the intra-S phase checkpoint in response to genotoxic stress.
Synonyms
TIMELESS-interacting protein|TIPIN
Gene ID
54962
UniProt
Q9BVW5
Host
Rabbit
Reactivity
Human
Immunogen
TIMELESS interacting protein
Target
TIPIN
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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