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THEM4 antibody

CAT: 0710-FNab08663Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08663Size:100 µg
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Background
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
Synonyms
Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) |Carboxyl-terminal modulator protein|Thioesterase superfamily member 4|THEM4|CTMP
Gene ID
117145
UniProt
Q5T1C6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Thioesterase superfamily member 4
Target
THEM4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
37-150aa

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