THEM4 antibody

• Background:

  Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.

• Synonyms:

  Acyl-coenzyme A thioesterase THEM4 (Acyl-CoA thioesterase THEM4) |Carboxyl-terminal modulator protein|Thioesterase superfamily member 4|THEM4|CTMP

• Gene ID:

  117145

• UniProt:

  Q5T1C6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Thioesterase superfamily member 4

• Target:

  THEM4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  26 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  37-150aa