TFAP2C antibody

• Background:

  Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

• Synonyms:

  Transcription factor AP-2 gamma (AP2-gamma) |Activating enhancer-binding protein 2 gamma|Transcription factor ERF-1|TFAP2C

• Gene ID:

  7022

• UniProt:

  Q92754

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

• Target:

  TFAP2C

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, FC, IP

• Field of Research:

  Cancer, Signal Transduction, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  50 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, FC, IP