TFAP2C antibody

CAT: 0710-FNab08619Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08619Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Synonyms
Transcription factor AP-2 gamma (AP2-gamma) |Activating enhancer-binding protein 2 gamma|Transcription factor ERF-1|TFAP2C
Gene ID
7022
UniProt
Q92754
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Target
TFAP2C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IP
Field of Research
Cancer, Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IP

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