TFAP2B antibody

• Background :

  Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.

• Synonyms :

  Transcription factor AP-2-beta (AP2-beta) |Activating enhancer-binding protein 2-beta|TFAP2B

• Gene ID :

  7021

• UniProt :

  Q92481

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

• Target :

  TFAP2B

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IP

• Field of Research :

  Cancer, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  50 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IP