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TELO2 antibody

CAT: 0710-FNab08592Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08592Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Regulator of the DNA damage response (DDR) . Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC) . Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.
Synonyms
Telomere length regulation protein TEL2 homolog|Protein clk-2 homolog (hCLK2) |TELO2|KIAA0683
Gene ID
9894
UniProt
Q9Y4R8
Host
Mouse
Reactivity
Human
Immunogen
TEL2, telomere maintenance 2, homolog
Target
TELO2
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, IHC, IF, IP, WB
Field of Research
Epigenetics
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:4000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
92 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8B6
Tested Applications
ELISA, IHC, IF, IP, WB

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