TBP antibody

CAT: 0710-FNab08527Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab08527Size:100 µg
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Background
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Synonyms
TATA-box-binding protein|TATA sequence-binding protein|TATA-binding factor|TATA-box factor|Transcription initiation factor TFIID TBP subunit|TBP|GTF2D1|TF2D|TFIID
Gene ID
6908
UniProt
P20226
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
TATA box binding protein
Target
TBP
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB, IP
Field of Research
Neuroscience, Metabolism, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:2000-1:5000; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
7B0
Tested Applications
ELISA, WB, IP

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