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TBL1X antibody

CAT: 0710-FNab08522Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08522Size:100 µg
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Background
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Synonyms
F-box-like/WD repeat-containing protein TBL1X|SMAP55|Transducin beta-like protein 1X|Transducin-beta-like protein 1, X-linked|TBL1X|TBL1
Gene ID
6907
UniProt
O60907
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Transducin (beta) -like 1X-linked
Target
TBL1X
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · O60907

F-box-like/WD repeat-containing protein TBL1X

TBL1X_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60907
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TBL1X
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K044, A8K4J7, Q86UY2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Activator

Coding sequence diversity

Alternative splicing

Disease

Congenital hypothyroidismDeafnessDisease variant

Cellular component

Nucleus

Domain

RepeatWD repeat

Biological process

TranscriptionTranscription regulationUbl conjugation pathway

Alternative Products