TAB2 antibody

• Background :

  Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.

• Synonyms :

  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2|Mitogen-activated protein kinase kinase kinase 7-interacting protein 2|TAK1-binding protein 2 (TAB-2) |TGF-beta-activated kinase 1-binding protein 2|TAB2|KIAA0733|MAP3K7IP2

• Gene ID :

  23118

• UniProt :

  Q9NYJ8

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Mitogen-activated protein kinase kinase kinase 7 interacting protein 2

• Target :

  TAB2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, IHC, IF, WB, FC, IP

• Field of Research :

  Immunology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  77 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, IHC, IF, WB, FC, IP