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SUPV3L1 antibody

CAT: 0710-FNab08397Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08397Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA.
Synonyms
ATP-dependent RNA helicase SUPV3L1, mitochondrial|Suppressor of var1 3-like protein 1 (SUV3-like protein 1) |SUPV3L1|SUV3
UniProt
Q8IYB8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Suppressor of var1, 3-like 1
Target
SUPV3L1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IP, WB

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