SUMO2/3 antibody

• Background:

  This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Synonyms:

  Small ubiquitin-related modifier 2 (SUMO-2) |HSMT3|SMT3 homolog 2|SUMO-3|Sentrin-2|Ubiquitin-like protein SMT3B (Smt3B) |SUMO2|SMT3B|SMT3H2

• Gene ID:

  6613

• UniProt:

  P61956

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  SMT3 suppressor of mif two 3 homolog 2

• Target:

  SUMO2/3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Epigenetics, Cell Division and Proliferation, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  11 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF