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STAMBP antibody

CAT: 0710-FNab08285Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08285Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Synonyms
STAM-binding protein|Associated molecule with the SH3 domain of STAM|Endosome-associated ubiquitin isopeptidase|STAMBP|AMSH
Gene ID
10617
UniProt
O95630
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
STAM binding protein
Target
STAMBP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · O95630

STAM-binding protein

STABP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O95630
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
STAMBP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.-
Processing
—
Secondary accessions
B5M0B6, D6W5H7, Q3MJE7
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndosomeMembraneNucleus

Disease

Disease variant

Molecular function

HydrolaseMetalloproteaseProtease

Ligand

Metal-bindingZinc

PTM

PhosphoproteinUbl conjugation

Biological process

Ubl conjugation pathway

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CSB-PA022794GA01HUSTAMBP Antibody

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