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SRRM1 antibody

CAT: 0710-FNab08242Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08242Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE) -dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.
Synonyms
Serine/arginine repetitive matrix protein 1|SR-related nuclear matrix protein of 160 kDa (SRm160) |Ser/Arg-related nuclear matrix protein|SRRM1|SRM160
Gene ID
10250
UniProt
Q8IYB3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serine/arginine repetitive matrix 1
Target
SRRM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120-160 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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