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SPIRE2 antibody

CAT: 0710-FNab08183Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08183Size:100 µg
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Background
Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.
Synonyms
Protein spire homolog 2 (Spir-2) |SPIRE2|KIAA1832|SPIR2
Gene ID
84501
UniProt
Q8WWL2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Spire homolog 2 (Drosophila)
Target
SPIRE2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q8WWL2

Protein spire homolog 2

SPIR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WWL2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPIRE2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Spir-2
EC number
—
Processing
—
Secondary accessions
A4QPB1, Q2TA98, Q6P433, Q8ND47, Q96JJ5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-binding

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleCytoskeletonMembrane

PTM

Phosphoprotein

Biological process

Protein transportTransport

Domain

Repeat

Alternative Products