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SPINK1 antibody

CAT: 0710-FNab08180Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08180Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173) . In the pancreas, protects against trypsin-catalyzed premature activation of zymogens (By similarity) . In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Synonyms
Serine protease inhibitor Kazal-type 1|Pancreatic secretory trypsin inhibitor|Tumor-associated trypsin inhibitor (TATI) |SPINK1|PSTI
Gene ID
6690
UniProt
P00995
Host
Rabbit
Reactivity
Human
Immunogen
Serine peptidase inhibitor, Kazal type 1
Target
SPINK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC

UniProtKB · P00995

Serine protease inhibitor Kazal-type 1

ISK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00995
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPINK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Disease variant

PTM

Disulfide bond

Molecular function

Protease inhibitorSerine protease inhibitor

Cellular component

Secreted

Domain

Signal

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