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SNRPD3 antibody

CAT: 0710-FNab08075Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab08075Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
Synonyms
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) |snRNP core protein D3|SNRPD3
Gene ID
6634
UniProt
P62318
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Small nuclear ribonucleoprotein D3 polypeptide 18kDa
Target
SNRPD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Neuroscience, Metabolism, Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
14 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P62318

Small nuclear ribonucleoprotein Sm D3

SMD3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P62318
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SNRPD3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Sm-D3
EC number
—
Processing
—
Secondary accessions
B4DJP7, B5BU13, P43331
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationMethylation

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleusSpliceosome

Biological process

mRNA processingmRNA splicing

Domain

Repeat

Molecular function

RibonucleoproteinRNA-binding

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