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SH3BP1 antibody

CAT: 0710-FNab07829Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07829Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity) .
Synonyms
SH3 domain-binding protein 1|SH3BP1
Gene ID
23616
UniProt
Q9Y3L3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
SH3-domain binding protein 1
Target
SH3BP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
76-80 kDa, 51 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

UniProtKB · Q9Y3L3

SH3 domain-binding protein 1

3BP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y3L3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SH3BP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5R3N0, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative initiationAlternative splicing

Cellular component

Cell junctionCell projectionCytoplasmNucleusTight junction

Molecular function

GTPase activation

Biological process

Phagocytosis

PTM

Phosphoprotein

Domain

SH3-binding

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