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SGK1 antibody

CAT: 0710-FNab07806Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07806Size:100 µg
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Background
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Synonyms
Serine/threonine-protein kinase Sgk1|Serum/glucocorticoid-regulated kinase 1|SGK1|SGK
Gene ID
6446
UniProt
O00141
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Serum/glucocorticoid regulated kinase 1
Target
SGK1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

UniProtKB · O00141

Serine/threonine-protein kinase Sgk1

SGK1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00141
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SGK1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
B7UUP7, B7UUP8, B7UUP9, B7Z5B2, E1P583, Q5TCN2, Q5TCN3, Q5TCN4, Q5VY65, Q9UN56
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Biological process

ApoptosisStress response

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmEndoplasmic reticulumMembraneMitochondrionNucleus

PTM

Disulfide bondPhosphoproteinUbl conjugation

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

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