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SESN3 antibody

CAT: 0710-FNab07761Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07761Size:100 µg
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Background
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway (PubMed:25263562) . May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity) . This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity) .
Synonyms
Sestrin-3|SESN3|SEST3
Gene ID
143686
UniProt
P58005
Host
Rabbit
Reactivity
Human
Immunogen
Sestrin 3
Target
SESN3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Cardiovascular
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
51-59 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P58005

Sestrin-3

SESN3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P58005
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SESN3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.11.1.-
Processing
—
Secondary accessions
B7Z7P9, Q96AD1
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

Oxidoreductase

Technical term

Proteomics identificationReference proteome

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