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SERPINB6 antibody

CAT: 0710-FNab07747Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07747Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity) . Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Synonyms
Serpin B6|Cytoplasmic antiproteinase (CAP) |Peptidase inhibitor 6 (PI-6) |Placental thrombin inhibitor|SERPINB6|PI6|PTI
Gene ID
5269
UniProt
P35237
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Serpin peptidase inhibitor, clade B (ovalbumin), member 6
Target
SERPINB6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
42 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · P35237

Serpin B6

SPB6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35237
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SERPINB6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2RBA8, Q59F97, Q5TD06, Q7Z2Y7, Q96J44, Q9UDI7
Protein keywords

PTM

AcetylationPhosphoprotein

Cellular component

Cytoplasm

Disease

DeafnessNon-syndromic deafness

Technical term

Direct protein sequencingProteomics identificationReference proteome

Molecular function

Protease inhibitorSerine protease inhibitor

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