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SELENOK antibody

CAT: 0710-FNab07704Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07704Size:100 µg
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Background
Required for Ca (2+) flux in immune cells and plays a role in T-cell proliferation and in T-cell and neutrophil migration. Involved in endoplasmic reticulum-associated degradation (ERAD) of soluble glycosylated proteins. Required for palmitoylation and cell surface expression of CD36 and involved in macrophage uptake of low-density lipoprotein and in foam cell formation. Plays a role in protection of cells from ER stress-induced apoptosis. Protects cells from oxidative stress when overexpressed in cardiomyocytes.
Synonyms
Selenoprotein K (SelK) |SELENOK|SELK
Gene ID
58515
UniProt
Q9Y6D0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Selenoprotein K
Target
SELENOK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
10 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q9Y6D0

Selenoprotein K

SELK_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y6D0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SELENOK
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SelK
EC number
—
Processing
—
Secondary accessions
Q8IZQ3, Q9P085
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Ligand

Calcium

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneEndoplasmic reticulumMembrane

Coding sequence diversity

Selenocysteine

Domain

TransmembraneTransmembrane helix

PTM

Ubl conjugation

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