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SECISBP2 antibody

CAT: 0710-FNab07695Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07695Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
Synonyms
Selenocysteine insertion sequence-binding protein 2 (SECIS-binding protein 2) |SECISBP2|SBP2
Gene ID
79048
UniProt
Q96T21
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
SECIS binding protein 2
Target
SECISBP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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