SAMHD1 antibody

• Background:

  Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.

• Synonyms:

  Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) |Dendritic cell-derived IFNG-induced protein (DCIP) |Monocyte protein 5 (MOP-5) |SAM domain and HD domain-containing protein 1 (hSAMHD1) |SAMHD1|MOP5

• Gene ID:

  25939

• UniProt:

  Q9Y3Z3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  SAM domain and HD domain 1

• Target:

  SAMHD1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IP, FC

• Field of Research:

  Immunology, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  64-72 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IP, FC