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SAMHD1 antibody

CAT: 0710-FNab07592Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07592Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling.
Synonyms
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) |Dendritic cell-derived IFNG-induced protein (DCIP) |Monocyte protein 5 (MOP-5) |SAM domain and HD domain-containing protein 1 (hSAMHD1) |SAMHD1|MOP5
Gene ID
25939
UniProt
Q9Y3Z3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SAM domain and HD domain 1
Target
SAMHD1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP, FC
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
64-72 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP, FC

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