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Recombinant Human SAMHD1

CAT: 0710-P2350-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P2350-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
DCIP, HDDC1, Monocyte protein 5, MOP 5, MOP5, SAM domain and HD domain 1, SAMHD1, SBBI88
UniProt
Q9Y3Z3
Expression Region
161-312
Host
E.Coli
Tag
N-terminal His-IF2DI Tag
Applications
Western Blot, ELISA
Field of Research
Immunology, Metabolism
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
37.9 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q9Y3Z3

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

SAMH1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y3Z3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SAMHD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
dNTPase
EC number
3.1.5.-
Processing
—
Secondary accessions
B4E2A5, E1P5V2, Q5JXG8, Q8N491, Q9H004, Q9H005, Q9H3U9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Disease

Aicardi-Goutieres syndromeDisease variant

Molecular function

Allosteric enzymeHydrolase

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseDNA damageDNA repairDNA replicationHost-virus interactionImmunityInnate immunity

Cellular component

ChromosomeNucleus

Ligand

GTP-bindingMetal-bindingNucleotide-bindingZinc

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