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RYK antibody

CAT: 0710-FNab07548Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07548Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Synonyms
Tyrosine-protein kinase RYK|RYK|JTK5A
Gene ID
6259
UniProt
P34925
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RYK receptor-like tyrosine kinase
Target
RYK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
68 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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