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RUFY1 antibody

CAT: 0710-FNab07528Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07528Size:100 µg
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Background
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
RUN and FYVE domain-containing protein 1|FYVE-finger protein EIP1|La-binding protein 1|Rab4-interacting protein|Zinc finger FYVE domain-containing protein 12|RUFY1|RABIP4|ZFYVE12
Gene ID
80230
UniProt
Q96T51
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RUN and FYVE domain containing 1
Target
RUFY1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q96T51

RUN and FYVE domain-containing protein 1

RUFY1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96T51
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RUFY1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q59FF3, Q71S93, Q9H6I3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilZinc-finger

Biological process

EndocytosisProtein transportTransport

Cellular component

EndosomeMembrane

Ligand

Lipid-bindingMetal-bindingZinc

PTM

Phosphoprotein

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