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RRAGB antibody

CAT: 0710-FNab07488Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07488Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
Synonyms
Ras-related GTP-binding protein B (Rag B, RagB) |RRAGB
Gene ID
10325
UniProt
Q5VZM2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Ras-related GTP binding B
Target
RRAGB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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