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RNF212 antibody

CAT: 0710-FNab07350Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07350Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins(MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination(By similarity).
CAS Number
9007-83-4
Synonyms
Probable E3 SUMO-protein ligase RNF212|Probable E3 SUMO-protein transferase RNF212|RING finger protein 212|RNF212
Gene ID
285498
UniProt
Q495C1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ring finger protein 212
Target
RNF212
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
22 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

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