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RNASET2 antibody

CAT: 0710-FNab07324Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07324Size:100 µg
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Background
RNASET2 (Ribonuclease T2) is also named as RNASE6PL (Ribonuclease 6) and belongs to the RNase T2 family. It is a unique member of the growing family of tumor-antagonizing genes and behaves as a class II tumor suppressor and abolish the tumorigenic potential of an ovarian cancer-derived cell line. This protein has 2 isoforms produced by alternative splicing. Both mildly glycosylated (ranging from38 to 45 kDa) and highly glycosylated forms (ranging from 50 to 80 kDa) of human tumor suppressor protein RNASET2 can be detected in immunoblotting
Synonyms
Ribonuclease T2|Ribonuclease 6|RNASET2|RNASE6PL
Gene ID
8635
UniProt
O00584
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Ribonuclease T2
Target
RNASET2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, WB, IP

UniProtKB · O00584

Ribonuclease T2

RNT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00584
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RNASET2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.6.1.19
Processing
Precursor
Secondary accessions
B2RDA7, E1P5C3, Q5T8Q0, Q8TCU2, Q9BZ46, Q9BZ47
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Molecular function

EndonucleaseHydrolaseLyaseNuclease

Cellular component

Endoplasmic reticulumLysosomeMitochondrionSecreted

Biological process

ImmunityInnate immunity

Domain

Signal

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