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RGS7 antibody

CAT: 0710-FNab07273Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07273Size:100 µg
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Background
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767) . The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509) . May play a role in synaptic vesicle exocytosis (PubMed:12659861) . Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264) .
Synonyms
Regulator of G-protein signaling 7 (RGS7) |RGS7
Gene ID
6000
UniProt
P49802
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Regulator of G-protein signaling 7
Target
RGS7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
62 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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