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RASGRP2 antibody

CAT: 0710-FNab07132Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07132Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.
Synonyms
RAS guanyl-releasing protein 2|Calcium and DAG-regulated guanine nucleotide exchange factor I (CalDAG-GEFI) |Cdc25-like protein (hCDC25L) |F25B3.3 kinase-like protein|RASGRP2|CDC25L|MCG7
Gene ID
10235
UniProt
Q7LDG7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
Target
RASGRP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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