RASGRP2 antibody

• Background:

  Functions as a calcium-and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.

• Synonyms:

  RAS guanyl-releasing protein 2|Calcium and DAG-regulated guanine nucleotide exchange factor I (CalDAG-GEFI) |Cdc25-like protein (hCDC25L) |F25B3.3 kinase-like protein|RASGRP2|CDC25L|MCG7

• Gene ID:

  10235

• UniProt:

  Q7LDG7

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  RAS guanyl releasing protein 2 (calcium and DAG-regulated)

• Target:

  RASGRP2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Neuroscience, Immunology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  48 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB