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RAD51 antibody

CAT: 0710-FNab07079Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07079Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308) . Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
Synonyms
DNA repair protein RAD51 homolog 1 (HsRAD51, hRAD51) |RAD51 homolog A|RAD51|RAD51A|RECA
Gene ID
5888
UniProt
Q06609
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RAD51 homolog
Target
RAD51
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP,IHC
Field of Research
Epigenetics, Cancer, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
37 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP, IHC

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