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PYCR1 antibody

CAT: 0710-FNab06970Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06970Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress.
Synonyms
Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1, P5CR 1) |PYCR1
Gene ID
5831
UniProt
P32322
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Pyrroline-5-carboxylate reductase 1
Target
PYCR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa, 35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · P32322

Pyrroline-5-carboxylate reductase 1, mitochondrial

P5CR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P32322
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PYCR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
P5C reductase 1, P5CR 1
EC number
1.5.1.2
Processing
—
Secondary accessions
A6NFM2, B4DMU0, Q6FHI4, Q96DI6, Q9HBQ4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Amino-acid biosynthesisProline biosynthesisStress response

Disease

Disease variant

Cellular component

Mitochondrion

Ligand

NADP

Molecular function

Oxidoreductase

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