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PTGDS antibody

CAT: 0710-FNab06914Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06914Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2) . PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Synonyms
Prostaglandin-H2 D-isomerase|Beta-trace protein|Cerebrin-28|Glutathione-independent PGD synthase|Lipocalin-type prostaglandin-D synthase (L-PGDS) |Prostaglandin-D2 synthase (PGD2 synthase, PGDS, PGDS2) |PTGDS|PDS
Gene ID
5730
UniProt
P41222
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Prostaglandin D2 synthase 21kDa (brain)
Target
PTGDS
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Signal Transduction, Metabolism, Cancer, Developmental biology, Neuroscience
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
21-28 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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