PSIP1 antibody

• Background:

  Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

• Synonyms:

  PC4 and SFRS1-interacting protein|CLL-associated antigen KW-7|Dense fine speckles 70 kDa protein (DFS 70) |Lens epithelium-derived growth factor|Transcriptional coactivator p75/p52|PSIP1|DFS70|LEDGF|PSIP2

• Gene ID:

  11168

• UniProt:

  O75475

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  PC4 and SFRS1 interacting protein 1

• Target:

  PSIP1

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Epigenetics, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  60 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB

• Immunogen Sequence:

  306-530aa