Products for Research Use Only
RegisterLogin

PRAME antibody

CAT: 0710-FNab06746Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab06746Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
Synonyms
Melanoma antigen preferentially expressed in tumors|Opa-interacting protein 4 (OIP-4) |Preferentially expressed antigen of melanoma|PRAME|MAPE|OIP4
Gene ID
23532
UniProt
P78395
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Preferentially expressed antigen in melanoma
Target
PRAME
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-58 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

UniProtKB · P78395

Melanoma antigen preferentially expressed in tumors

PRAME_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78395
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRAME
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R6Y7, O43481, Q8IXN8
Protein keywords

Biological process

ApoptosisDifferentiationGrowth regulationTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

Cell membraneChromosomeCytoplasmGolgi apparatusMembraneNucleus

Domain

Leucine-rich repeatRepeat

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Molecular function

Repressor

Related Products

CatalogName
P5558-01Recombinant Human PRAME
EH1290Human PRAME (Melanoma antigen preferentially expressed in tumors) ELISA Kit
FNab06745PRAM1 antibody
FNab11062CA125 antibody (capture antibody)
FNab11060AFP antibody (capture antibody)
FNab11045-01CEA antibody (detection antibody)
FNab11061CA125 antibody (detection antibody)
FNab11059AFP antibody (detection antibody)
FNab11046-01CEA antibody (capture antibody)
FNab09471WAS antibody

Alternative Products

CatalogName
MBS9416944-01PRAME Antibody

Popular Products