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PINX1 antibody

CAT: 0710-FNab06460Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06460Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.
Synonyms
PIN2/TERF1-interacting telomerase inhibitor 1|Liver-related putative tumor suppressor|Pin2-interacting protein X1|Protein 67-11-3|TRF1-interacting protein 1|PINX1|LPTL|LPTS
Gene ID
54984
UniProt
Q96BK5
Host
Rabbit
Reactivity
Human
Immunogen
PIN2-interacting protein 1
Target
PINX1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDaa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

UniProtKB · Q96BK5

PIN2/TERF1-interacting telomerase inhibitor 1

PINX1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96BK5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PINX1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R9B1, Q548A5, Q6QWG9, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CentromereChromosomeKinetochoreNucleusTelomere

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Disease

Tumor suppressor

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