PHOX2B antibody

• Background :

  Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

• Synonyms :

  Paired mesoderm homeobox protein 2B|Neuroblastoma Phox (NBPhox) |PHOX2B homeodomain protein|Paired-like homeobox 2B|PHOX2B|PMX2B

• Gene ID :

  8929

• UniProt :

  Q99453

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Paired-like homeobox 2b

• Target :

  PHOX2B

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF, IHC

• Field of Research :

  Neuroscience, Epigenetics, Metabolism, Developmental biology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  31 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF, IHC