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PELI1 antibody

CAT: 0710-FNab06303Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06303Size:100 µg
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Background
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation.
Synonyms
E3 ubiquitin-protein ligase pellino homolog 1 (Pellino-1) |Pellino-related intracellular-signaling molecule|RING-type E3 ubiquitin transferase pellino homolog 1|PELI1|PRISM
Gene ID
57162
UniProt
Q96FA3
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Pellino homolog 1 (Drosophila)
Target
PELI1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
46 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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