PEG10 antibody

• Background :

  Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity) . May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity) .

• Synonyms :

  Retrotransposon-derived protein PEG10|Embryonal carcinoma differentiation-regulated protein|Mammalian retrotransposon-derived protein 2|Myelin expression factor 3-like protein 1 (MEF3-like protein 1) |Paternally expressed gene 10 protein|Retrotransposon gag domain-containing protein 3|Retrotransposon-derived gag-like polyprotein|Ty3/Gypsy-like protein|PEG10|EDR|KIAA1051e|MAR2|MART2|MEF3L1|RGAG3

• Gene ID :

  23089

• UniProt :

  Q86TG7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Paternally expressed 10

• Target :

  PEG10

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF

• Field of Research :

  Stem Cells, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  50 kDa, 100 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF