PDE5A antibody

• Background:

  Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334) . Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334) .

• Synonyms:

  CGMP-specific 3',5'-cyclic phosphodiesterase|cGMP-binding cGMP-specific phosphodiesterase (CGB-PDE) |PDE5A|PDE5

• Gene ID:

  8654

• UniProt:

  O76074

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Phosphodiesterase 5A, cGMP-specific

• Target:

  PDE5A

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IF

• Field of Research:

  Cardiovascular, Metabolism, Developmental biology, Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IF: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  100 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IF

• Immunogen Sequence:

  1-150aa