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PDE5A antibody

CAT: 0710-FNab06256Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06256Size:100 µg
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Background
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:9714779, PubMed:15489334) . Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334) .
Synonyms
CGMP-specific 3',5'-cyclic phosphodiesterase|cGMP-binding cGMP-specific phosphodiesterase (CGB-PDE) |PDE5A|PDE5
Gene ID
8654
UniProt
O76074
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Phosphodiesterase 5A, cGMP-specific
Target
PDE5A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Cardiovascular, Metabolism, Developmental biology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
100 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
Immunogen Sequence
1-150aa

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